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Five home-care formulas and one professional protocol for oily, congested and breakout-prone skin. Cortisol control, needle-free.
Arriving September 2026 — have your routine prescribed at a SKEYNDOR+ salon.
Under pressure, skin makes more cortisol — the stress hormone. Cortisol is where the oil, the congestion and the breakouts begin.
Congestion and breakouts have four drivers in the pore. CLEARIST CTX answers every one.
When the cells lining the pore over-produce, they obstruct it — the first step toward congestion.
Exfoliating Care Lotion
Androgens drive excess oil and shine. The enzyme 5-alpha reductase is the switch that keeps it flowing.
Mattifying GBX Booster
The bacteria behind breakouts are normal residents — until an oil-rich, blocked follicle lets them proliferate and inflame.
Instant Correcting Gel
Blockage, altered oil and bacteria trigger inflammation — and, over time, marks and recurrence.
Mattifying Balance Gel-Emulsion
Fresh, non-comedogenic textures — each built for a step in the day, and prescribed for your skin.
Step 1 · CleanseUnclogs and gently exfoliates in one step — lifting oil and impurities, easing shine, no tightness. AM & PM.
Step 2 · DayRegulates oil without drying — purifying from the first use. GABA works needle-free to refine pores and hold back shine. AM.
Step 2 · NightA gentle daily peel (10% AHA) that refines pores and softens the look of marks — with an anti-cortisol action from Tephrosia. PM.
Step 3 · HydrateThe hydrator — rebalances barrier and microbiome, calms skin unsettled by acids or vitamin-A, and finishes matte. AM & PM.
Targeted · SOSDab onto a single blemish. Dries fast, forms an invisible film like a patch, and helps it fade without marks. Anytime, up to 3× daily.
Your therapist reads your skin and builds the exact routine. Find a salon to have yours prescribed.
Find a salonSame cleanse, same finish — the middle step changes with the light.
Aesthetic-medicine mechanisms meet the science of psychodermatology. A few of the actives at work:
The botanical the CTX is named for. It regulates how skin cells make cortisol — the driver of oil and inflammation, and the one point everything else ignores.
GABA is a neuro-relaxing amino acid that eases oil to the surface — needle-free. Sarcosine quiets 5-alpha reductase, the enzyme behind over-production.
Instead of stripping the skin, it trains the skin's own antimicrobial defences — reinforcing innate immunity against breakout bacteria.
An anti-androgenic, antibacterial 5-alpha reductase inhibitor — regulating oil and calming the environment breakouts thrive in.
Mandelic, succinic, glycolic and gluconolactone (PHA). Low-solubility acids concentrate inside the pore — refining texture with minimal irritation.
Lens esculenta normalises how pore-lining cells mature and shed, so oil flows freely — visibly refining the appearance of enlarged pores.


Twice across the course, the routine goes professional — an hour under the DermaLED canopy, blue light to purify at the surface, red to calm and restore below. The half a jar can't give you.
VISIA and VISIOSCAN imaging on 21 people — young and adult — with blemish-prone, oily and combination skin. Five weeks on the complete protocol.
Instrumental study, 21 volunteers, combination/oily blemish-prone skin. Five weeks of the complete CLEARIST CTX protocol — the home-care range plus two in-salon treatments with DERMALED XPERT. VISIA skin analysis; sebaceous activity by VISIOSCAN VC 20 PLUS + SEBUFIX. Results refer to the full protocol, not to any single product. Cosmetic treatment — not a medical therapy.
Before
After
The same skin on the complete CLEARIST CTX protocol — home-care range plus in-salon sessions. Individual results vary.
Have your skin read and your routine prescribed at a SKEYNDOR+ salon — then keep it going at home with the range.